Since space (length) is short, crossing loops do not normally have an overlap (safety margin) between the starting signals and the end of the double line.
It was found that the angle of the surface was well inside the safety margin (about 18 degrees), and the full excursion toward the rock layer of interest was started.
Under the conditions of this study, at least a twofold (vestibular) to fourfold (cochlear) relative safety margin for ototoxicity was established in favor of netilmicin over tobramycin and gentamicin.
