Endoscopic therapy with botulinum toxin, known also as Botox, can also be used to temporarily improve symptoms, but the effect is temporarily and may only last a few weeks.
Clinical trials have focused on understanding tic suppression, comorbid conditions, novel treatment approaches such as botulinum toxin, and targeted behavioral therapies.
Physical therapy, including the use of splints can help to prevent contractures, although injections of botulinum toxin (Botox) and surgery are sometimes required.