All currently used anthrax vaccines show considerable local and general reactogenicity (erythema, induration, soreness, fever) and serious adverse reactions occur in about 1% of recipients.
Minor complications include bruising (51%), hematoma (2.3%), temporary numbness (3.8%), phlebitis (7.4%), induration (46.7%), and a sensation of tightness (24.8%).
A condition called drug-induced ulcer of the lip is described as being characterized by painful or tender, well-defined ulcerations of the lip without induration.
