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bilirubin

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In the gut, brush border -glucuronidase converts conjugated bilirubin to the unconjugated form for reabsorption. en.wikipedia.org

This causes an accumulation of bilirubin in the blood (hyperbilirubinemia), leading to the symptoms of jaundice. en.wikipedia.org

Because this bilirubin is not soluble, however, it is transported through the blood bound to serum albumin. en.wikipedia.org

Prolonged jaundice or elevated bilirubin can present at birth. en.wikipedia.org

Bilirubin, for instance, is highly fluorescent when bound to a specific site on serum albumin. en.wikipedia.org

Total and direct bilirubin levels can be measured from the blood, but indirect bilirubin is calculated from the total and direct bilirubin. en.wikipedia.org

The hydrophilic character of bilirubin diglucuronide enables it to be water-soluble. en.wikipedia.org

In the intestine, bilirubin is converted by bacteria to stercobilinogen. en.wikipedia.org

Jaundice is caused by hyperbilirubinemia, or abnormally high levels of bilirubin in the blood. en.wikipedia.org

Obstruction of bilirubin passage into the gut or failure of urobilinogen production in the gut. en.wikipedia.org

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