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anaphase [Brit ˈanəfeɪz, Am ˈænəˌfeɪz] N

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Once activated, the spindle checkpoint blocks anaphase entry by inhibiting the anaphase-promoting complex via regulation of the activity of mitotic checkpoint complex. en.wikipedia.org

In the anaphase of mitosis, sister chromatids separate and migrate to opposite cell poles before the cell divides. en.wikipedia.org

For example, predivision (the separation of chromatids before anaphase) in the first polar body can induce the formation of an aneuploid polar body. en.wikipedia.org

The extra X chromosome results from either meiotic nondisjunction, in which a chromosome pair fails to separate during meiosis, or from anaphase lag. en.wikipedia.org

If some chromosomes are not properly attached to the mitotic spindle by the time of this checkpoint, the onset of anaphase will be delayed. en.wikipedia.org

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