The respiratory replication will result in loss of ciliary activity, mucus accumulation, necrosis and desquamation, causing respiratory distress, rles and asphyxia.
If a patient survives, recovery may be prompt and complete, or protracted with sequelae, such as orchitis, hepatitis, uveitis, parotitis, desquamation or alopecia.
Symptoms include desquamation or peeling, weak peripheral pulses, loss of peripheral sensation, edema and ultimately the death and loss of affected tissues.